Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels tumour heterogeneity plus M2-like tumour-associated macrophage infiltration and aggressiveness in TNBC
Xuanwen Bao, Run Shi, Tianyu Zhao, Yanfang Wang, Nataša Anastasov, Michael Rosemann, Weijia Fang
Topics & Concepts
Gene signatureTranscriptomeImmunotherapyBiologyImmune systemCancer researchTumour heterogeneityAngiogenesisCancer immunotherapySingle-cell analysisBreast cancerCellTriple-negative breast cancerGene expression profilingComputational biologyGeneCancerGene expressionImmunologyGeneticsSingle-cell and spatial transcriptomicsImmune cells in cancerCancer Immunotherapy and Biomarkers