Surgery Versus Stereotactic Radiotherapy for Treatment of Pulmonary metastases. a Systematic Review of Literature
Francesco Londero, William Grossi, Angelo Morelli, Orlando Parise, Gianluca Masullo, Cecilia Tetta, Ugolino Livi, Jos G. Maessen, Sandro Gelsomino
Abstract
It is not clear as to which is the best treatment among surgery and stereotactic radiotherapy (SBRT) for lung oligometastases. A systematic review of literature with a priori selection criteria was conducted on articles on the treatment of pulmonary metastases with surgery or SBRT. Only original articles with a population of patients of more than 50 were selected. After final selection, 61 articles on surgical treatment and 18 on SBRT were included. No difference was encountered in short-term survival between pulmonary metastasectomy and SBRT. In the long-term surgery seems to guarantee better survival rates. Mortality and morbidity after treatment are 0–4.7% and 0–23% for surgery, and 0–2% and 4–31% for SBRT. Surgical metastasectomy remains the treatment of choice for pulmonary oligometastases.