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Ongoing Challenges in the Diagnosis of Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease

Patrick Lipps, Ana Beatriz Ayroza Galvão Ribeiro Gomes, Laila Kulsvehagen, Matthias A. Mutke, Jens Kühle, Athina Papadopoulou, Anne‐Katrin Pröbstel

2023JAMA Neurology13 citationsDOIOpen Access PDF

Abstract

This cross-sectional study examines whether proposed myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) diagnostic criteria can exclude other diseases, such as multiple sclerosis, and rely on results of cell-based assays.

Topics & Concepts

Myelin oligodendrocyte glycoproteinMultiple sclerosisOligodendrocyteMyelinDiseaseAntibodyImmunologyMedicineGlycoproteinDemyelinating diseaseMyelin-associated glycoproteinPathologyBiologyCentral nervous systemInternal medicineGeneticsExperimental autoimmune encephalomyelitisMultiple Sclerosis Research StudiesPeripheral Neuropathies and DisordersNeurogenesis and neuroplasticity mechanisms
Ongoing Challenges in the Diagnosis of Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease | Litcius