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Nickel-catalyzed electrochemical reductive relay cross-coupling of alkyl halides with alkyl carboxylic acids

Ke‐Jin Jiao, Cong Ma, Dong Liu, Hui Qiu, Bin Cheng, Tian‐Sheng Mei

2021Organic Chemistry Frontiers30 citationsDOI

Abstract

A highly regioselective Ni-catalyzed electrochemical (undivided cell) reductive relay cross-coupling between alkyl carboxylic acids and alkyl bromides has been developed.

Topics & Concepts

AlkylChemistryHalideNickelCatalysisRegioselectivityElectrochemistryCoupling (piping)Carboxylic acidOrganic chemistryCombinatorial chemistryElectrodeMetallurgyMaterials sciencePhysical chemistryRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling Reactions
Nickel-catalyzed electrochemical reductive relay cross-coupling of alkyl halides with alkyl carboxylic acids | Litcius