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Implications of the 2023–2024 MPXV clade I outbreak in the Democratic Republic of Congo to global public health

Angel N. Desai, Marion Koopmans, Ashley Otter, Martin P. Grobusch, Pikka Jokelainen, Barry Atkinson, Flávia Cunha, Sofia R. Valdoleiros, Veronica G. Preda, Francesco Maria Fusco, Chantal P. Bleeker‐Rovers, Gilbert Greub, Antonino Di, Lone Simonsen, Francine Ntoumi, Eskild Petersen

2024Clinical Microbiology and Infection15 citationsDOIOpen Access PDF

Abstract

Mpox, a zoonotic disease resulting from infection with monkeypox virus (MPXV), was previously considered endemic to central- and west Africa. However, an ongoing global outbreak of clade IIb (previously known as West African clade) MPXV associated with human-to-human transmission primarily through sexual contact has occurred since May 2022, with introduction of MPXV to regions and countries that had previously only reported sporadic imported cases [ 1 Thornhill J.P. et al. Monkeypox Virus Infection in Humans across 16 Countries - April-June 2022. N. Engl. J. Med. Jul. 2022; Crossref Scopus (1114) Google Scholar ], [ 2 Laurenson-Schafer H. et al. Description of the first global outbreak of mpox: an analysis of global surveillance data. Lancet Glob. Health. Jul. 2023; 11: e1012-e1023 Abstract Full Text Full Text PDF PubMed Scopus (0) Google Scholar ].

Topics & Concepts

OutbreakCladePublic healthEnvironmental healthGeographyMedicineBiologyVirologyPhylogeneticsPathologyGeneticsGenePoxvirus research and outbreaksHerpesvirus Infections and TreatmentsBacillus and Francisella bacterial research