Casticin induces ferroptosis in human osteosarcoma cells through Fe2+ overload and ROS production mediated by HMOX1 and LC3-NCOA4
Habu Jiwa, Xie Zhou, Xiao Qu, Jingtao Xu, Yanran Huang, Xiongjie Huang, Jun Zhang, Nan Wang, Ningdao Li, Jinyong Luo, Xiaoji Luo
Abstract
overload and ROS production mediated by HMOX1 and LC3-NCOA4. This provides a new strategy for osteosarcoma treatment.
Topics & Concepts
OsteosarcomaFlow cytometryMTT assayCancer researchApoptosisStainingIn vitroChemistryMalignancyMolecular biologyBiologyPathologyMedicineBiochemistryFerroptosis and cancer prognosisCancer, Lipids, and MetabolismCircular RNAs in diseases