Lactoferrin docking NIR-II cyanine dye as a potentiated phototheranostic for synchronous multimodal bioimaging and tumor photo-immunotherapy
Lifeng Hang, Haijian Li, Meng Li, Yiqiang Sun, Wenjiao Wu, Laiping Fang, Yanzhao Diao, Qu Hong, Tao Zhang, Shumei Li, Guihua Jiang
Abstract
Lf@IR-1048 displays a powerful combination of photothermal therapy, photodynamic therapy, and tumor-targeting potential for effective multimodal imaging-guided NIR-II phototherapy, leading to substantial inhibition of tumor growth.
Topics & Concepts
CyanineLactoferrinChemistryImmunotherapyCancer researchDocking (animal)Combinatorial chemistryNanotechnologyBiochemistryMedicineMaterials scienceImmune systemImmunologyNursingQuantum mechanicsPhysicsFluorescenceNanoplatforms for cancer theranosticsImmunotherapy and Immune ResponsesRNA Interference and Gene Delivery