Highly regioselective oxidation of C–H bonds in water using hydrogen peroxide by a cytochrome P450 mimicking iron complex
Sandipan Jana, Puja De, Chinmay Dey, Somdatta Ghosh Dey, Abhishek Dey, Sayam Sen Gupta
Abstract
Development of a molecular iron complex, which via oxoiron( v ) formation, catalyzes highly efficient and regioselective oxidation of C–H bonds in water using hydrogen peroxide, and thereby acts as a functional model of cytochrome P450.
Topics & Concepts
ChemistrySelectivityRegioselectivityHydrogen peroxideHydrogen bondReactivity (psychology)Cytochrome P450CatalysisMoleculePeroxideStereochemistryMedicinal chemistryPhotochemistryCombinatorial chemistryEnzymeOrganic chemistryMedicineAlternative medicinePathologyMetal-Catalyzed Oxygenation MechanismsPharmacogenetics and Drug MetabolismOxidative Organic Chemistry Reactions