Carrier-free nanoparticles based on natural products trigger dual "synergy and attenuation" for enhanced phototherapy of liver cancer
Xiongqin Wang, Kunhui Sun, Junlin Dong, Yanli Ge, Haifan Liu, Xingyue Jin, Xiao Pei, Ping Wang, Jianbing Jiang, Tiejie Wang, Xuelei Hu, Shuguang Yuan, Bing Wang, Xie‐an Yu
Abstract
experiments demonstrated that GGZ NPs exhibit significant liver-targeting ability and could reduce the liver toxicity induced by gambogic acid, as well as decrease the blood biochemical levels of AST and ALT, achieving externally assisted "synergism and attenuation". Hence, carrier-free nanoparticles based on natural products would bring a new treatment modality to the field of precision liver tumor therapy.
Topics & Concepts
Dual (grammatical number)AttenuationLiver cancerNatural (archaeology)CancerNanotechnologyMedicineMaterials scienceInternal medicinePhysicsBiologyOpticsArtPaleontologyLiteratureNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryCurcumin's Biomedical Applications