5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
Shuni Wang, Hong Yang, Mingbo Su, Fulin Lian, Zhanqing Cong, Rongrui Wei, Yubo Zhou, Xingjun Li, Xingling Zheng, Chunpu Li, Xuhong Fu, Xu Han, Qiongyu Shi, Cong Li, Naixia Zhang, Meiyu Geng, Hong Liu, Jia Li, Xun Huang, Jiang Wang
Topics & Concepts
ChemistryHistone H3Histone methyltransferaseMethyltransferaseHistoneMethylationCell cultureCell growthHistone methylationCancer researchDNA methylationMolecular biologyBiochemistryGeneGene expressionBiologyGeneticsCancer-related gene regulationProtein Degradation and InhibitorsEpigenetics and DNA Methylation