Litcius/Paper detail

Inhibition of BTK improved APAP-induced liver injury via suppressing proinflammatory macrophages activation by restoring mitochondrion function

Huiting Guo, Mingjie Xie, Weixia Liu, Shiwei Chen, Bingjue Ye, Jiping Yao, Zhengyun Xiao, Cheng Zhou, Min Zheng

2022International Immunopharmacology16 citationsDOI

Topics & Concepts

Proinflammatory cytokineMitochondrionBruton's tyrosine kinaseFunction (biology)ChemistryPharmacologyCancer researchCell biologyMedicineImmunologyInflammationBiologySignal transductionTyrosine kinaseDrug-Induced Hepatotoxicity and ProtectionHepatitis C virus researchinterferon and immune responses