Mechanistic insight into <i>anti</i>-carbometalation of an alkyne <i>via</i> η<sup>2</sup>-vinyl-nickel type <i>Z</i>/<i>E</i> isomerization
Chunhui Shan, Miaomiao He, Xiaoling Luo, Rong Li, Tao Zhang
Abstract
In this reaction, η 2 -vinyl-nickel type Z / E isomerization is found to be lower in energy compared with carbonyl-assisted Z / E isomerization from a syn -alkenylnickel intermediate.
Topics & Concepts
IsomerizationChemistryAlkyneNickelMedicinal chemistryPhotochemistryOrganic chemistryCatalysisOrganometallic Complex Synthesis and CatalysisCarbon dioxide utilization in catalysisCatalytic Alkyne Reactions