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Design, synthesis, and biological evaluation of new series of pyrrol-2(3H)-one and pyridazin-3(2H)-one derivatives as tubulin polymerization inhibitors

Mahmoud S. Abdelbaset, Mostafa Abdelrahman, Syed Nasir Abbas Bukhari, Ahmed M. Gouda, Bahaa G. M. Youssif, Mohamed Abdel‐Aziz, Gamal El‐Din A. Abuo‐Rahma

2020Bioorganic Chemistry16 citationsDOI

Topics & Concepts

TubulinChemistryStereochemistryMicrotubuleDocking (animal)MedicineBiologyNursingCell biologySynthesis and Reactivity of HeterocyclesSynthesis and biological activityCancer therapeutics and mechanisms
Design, synthesis, and biological evaluation of new series of pyrrol-2(3H)-one and pyridazin-3(2H)-one derivatives as tubulin polymerization inhibitors | Litcius