Litcius/Paper detail

Gut Microbiome and Depression: How Microbes Affect the Way We Think

Therese Limbana, Farah Khan, Noha Eskander

2020Cureus118 citationsDOIOpen Access PDF

Abstract

The gut microbiome serves an important role in the human body. Reportedly, one of the benefits of these microflora is on mental health. Once established, food and other dietary sources that enhance quality microbiome content in our gastrointestinal system will be a significant consideration in individuals' day to day lives. This literature review conducted a PubMed search for studies about the gut microbiome and its relation to depression. In using several Medical Subject Heading (MeSH) keywords, relevant literature was selected. A total of 26 articles were selected after applying the inclusion and exclusion criteria, and after checking the articles' accessibility. This literature would like to establish the role of the gut microbiome in depression. This study's findings showed that there is a strong association of microbiome function to mental well-being.

Topics & Concepts

MicrobiomeGut microbiomeMedicineAffect (linguistics)Depression (economics)Mental healthPsychiatryBioinformaticsBiologyPsychologyCommunicationMacroeconomicsEconomicsGut microbiota and healthDiet and metabolism studiesTryptophan and brain disorders