Difunctionalization of <i>gem</i>-difluoroalkenes for amination and heteroarylation <i>via</i> metal-free photocatalysis
Yuanchen Zhong, Zhen Zhuang, Xiaofei Zhang, Bin Xu, Chunhao Yang
Abstract
radical-radical cross-coupling in energy-transfer-mediated photocatalysis and can be used in the rapid construction of heteroaryl difluoroethylamine scaffolds and late-stage modification of complex pharmaceutical structures.
Topics & Concepts
AminationPhotocatalysisChemistryMetalCombinatorial chemistryOrganic chemistryCatalysisFluorine in Organic ChemistryRadical Photochemical ReactionsSynthesis and Catalytic Reactions