Litcius/Paper detail

Uncertainty quantification for misspecified machine learned interatomic potentials

Danny Pérez, Aparna P. A. Subramanyam, Ivan Maliyov, Thomas D. Swinburne

2025npj Computational Materials7 citationsDOIOpen Access PDF

Abstract

Abstract The use of high-dimensional regression techniques from machine learning has significantly improved the quantitative accuracy of interatomic potentials. Atomic simulations can now plausibly target quantitative predictions in a variety of settings, which has brought renewed interest in robust means to quantify uncertainties. In many practical settings where model complexity is constrained (e.g., due to performance considerations), misspecification — the inability of any one choice of model parameters to exactly match all training data — is a key contributor to errors that is often disregarded. Here, we employ a recent misspecification-aware regression technique to quantify parameter uncertainties, which is then propagated to a broad range of phase and defect properties in tungsten. The propagation is performed through both brute-force resampling and implicit Taylor expansion. The propagated misspecification uncertainties robustly quantify and bound errors on a broad range of material properties. We demonstrate application to recent foundational machine learning interatomic potentials, accurately predicting and bounding errors in MACE-MPA-0 energy predictions across the diverse materials project database.

Topics & Concepts

Computer scienceMachine Learning in Materials ScienceFault Detection and Control SystemsComputational Drug Discovery Methods