Litcius/Paper detail

Deep learning for RNA structure prediction

Jiuming Wang, Yimin Fan, Liang Hong, Zhihang Hu, Yu Li

2025Current Opinion in Structural Biology18 citationsDOIOpen Access PDF

Abstract

Predicting RNA structures from sequences with computational approaches is of vital importance in RNA biology considering the high costs of experimental determination. AI methods have revolutionized this field in recent years, enabling RNA structure prediction with increasingly higher accuracy and efficiency. With an increase in the number of models proposed for this task, this review presents a timely summary of the applications of AI, particularly deep learning, in RNA structure prediction, highlighting their methodology advances as well as the challenges and opportunities for further work in this field.

Topics & Concepts

Computational biologyRNAArtificial intelligenceDeep learningComputer scienceBiologyGeneticsGeneRNA and protein synthesis mechanismsRNA modifications and cancerProtein Structure and Dynamics