Visible‐Light‐Induced Intramolecular Double Dearomative Cycloaddition of Arenes
Min Zhu, Hao Xu, Xiǎo Zhang, Chao Zheng, Shu‐Li You
Abstract
Herein we report visible-light-induced intramolecular double dearomative cycloaddition of arenes. Compared with the well-known photodimerization of arenes under ultraviolet irradiation, the current reactions are carried out under mild conditions and feature wide substrate scope. A large array of structurally-diverse polycyclic indoline derivatives is afforded in high yields (up to 98 %) with exclusive diastereoselectivity (>20:1 dr) via dearomative [4+2] or [2+2] pathway.
Topics & Concepts
Intramolecular forceCycloadditionIndolinePhotochemistryChemistrySubstrate (aquarium)Combinatorial chemistryStereochemistryOrganic chemistryCatalysisBiologyEcologyRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques