Overexpressed VLA-4 on endothelial cell membrane camouflaging the pathological reactive oxygen species responsive prodrug to enhance target therapy for atherosclerosis
Yuan Zhong, Kai Qu, Wenhua Yan, Kun Zhang, Xian Qin, Yi Wang, Meng Yan, Shuai Wu, Li Zhu, Essam Abdo Mohammed Saad Obaid, Guixue Wang, Wei Wu
Topics & Concepts
Reactive oxygen speciesChemistryDrug deliveryProdrugIn vivoCell biologyDownregulation and upregulationIn vitroPharmacologyCancer researchBiochemistryBiologyOrganic chemistryBiotechnologyGeneNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsCell Adhesion Molecules Research