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Blood pressure reduction and all-cause dementia in people with uncontrolled hypertension: an open-label, blinded-endpoint, cluster-randomized trial

Jiang He, Chuansheng Zhao, Shanshan Zhong, Nanxiang Ouyang, Guozhe Sun, Lixia Qiao, Ruihai Yang, Chunxia Zhao, Huayan Liu, Weiyu Teng, Xu Liu, Chang Wang, Songyue Liu, Chung-shiuan Chen, Jeff D. Williamson, Yingxian Sun

2025Nature Medicine40 citationsDOI

Topics & Concepts

DementiaMedicineOpen labelBlood pressureRandomized controlled trialClinical endpointDouble blindedCluster (spacecraft)Internal medicinePathologyDiseaseAlternative medicinePlaceboComputer scienceProgramming languageBlood Pressure and Hypertension StudiesDementia and Cognitive Impairment ResearchIntensive Care Unit Cognitive Disorders
Blood pressure reduction and all-cause dementia in people with uncontrolled hypertension: an open-label, blinded-endpoint, cluster-randomized trial | Litcius