Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans
Liam Chung, David R. Maestas, Andriana Lebid, Ashlie Mageau, Gedge D. Rosson, Xinqun Wu, Matthew T. Wolf, Ada Tam, Isabel Vanderzee, Xiaokun Wang, James I. Andorko, Hong Zhang, Radhika Narain, Kaitlyn Sadtler, Hongni Fan, Daniela Čiháková, Claude Jourdan Le Saux, Franck Housseau, Drew M. Pardoll, Jennifer H. Elisseeff
Abstract
17 immune response and the senescence response to implanted synthetic materials introduces new targets for therapeutic intervention in the foreign body response.
Topics & Concepts
InterleukinCell biologyBiologyMedicineImmunologyCytokineTelomeres, Telomerase, and SenescencePluripotent Stem Cells ResearchBiomedical Ethics and Regulation