Litcius/Paper detail

A machine learning model for ranking candidate HLA class I neoantigens based on known neoepitopes from multiple human tumor types

Jared J. Gartner, Maria R. Parkhurst, Alena Gros, Eric Tran, Mohammad Jafferji, Amy R. Copeland, Ken‐ichi Hanada, Nikolaos Zacharakis, Almin Lalani, Sri Krishna, Abraham Sachs, Todd D. Prickett, Yong F. Li, Maria Florentin, Scott Kivitz, Samuel C. Chatmon, Steven A. Rosenberg, Paul F. Robbins

2021Nature Cancer85 citationsDOIOpen Access PDF

Topics & Concepts

Human leukocyte antigenMajor histocompatibility complexMHC class IComputational biologyRanking (information retrieval)EpitopeBiologyImmunologyComputer scienceImmune systemMachine learningArtificial intelligenceAntigenvaccines and immunoinformatics approachesImmunotherapy and Immune ResponsesCAR-T cell therapy research