Abdominal Pain in Inflammatory Bowel Disease: An Evidence-Based, Multidisciplinary Review
Matthew Coates, Kofi Clarke, Emmanuelle Williams, Nimalan A. Jeganathan, Sanjay Kumar Yadav, David Giampetro, Vitaly Gordin, Sadie Smith, Kent E. Vrana, Anne D. Bobb, Thu Thi Gazzio, Heather Tressler, Shannon Dalessio
Abstract
Abdominal pain is one of the most common and impactful symptoms associated with inflammatory bowel disease (IBD), including both Crohn's disease and ulcerative colitis. A great deal of research has been undertaken over the past several years to improve our understanding and to optimize management of this issue. Unfortunately, there is still significant confusion about the underlying pathophysiology of abdominal pain in these conditions and the evidence underlying treatment options in this context. There is also a relative paucity of comprehensive reviews on this topic, including those that simultaneously evaluate pharmacological and nonpharmacological therapeutic options. In this review, our multidisciplinary team examines evidence for various currently available medical, surgical, and other analgesic options to manage abdominal pain in IBD.