Acidity and nucleophilic reactivity of glutathione persulfide
Dayana Benchoam, Jonathan A. Semelak, Ernesto Cuevasanta, Mauricio Mastrogiovanni, Juan Santiago Grassano, Gerardo Ferrer‐Sueta, Ari Zeida, Madia Trujillo, Matías N. Möller, Darío A. Estrı́n, Beatriz Álvarez
Abstract
of a biological persulfide and the first examination of the α effect in sulfur nucleophiles, and sheds light on the chemical basis of the biological properties of persulfides.
Topics & Concepts
ChemistryNucleophileGlutathioneReactivity (psychology)ElectrophileThiolMedicinal chemistryStereochemistryOrganic chemistryEnzymeCatalysisAlternative medicineMedicinePathologySulfur Compounds in BiologyRedox biology and oxidative stressElectron Spin Resonance Studies