The basics of commonly used molecular techniques for diagnosis, and application of molecular testing in cytology
Scott A. Turner, Rand Abou Shaar, Zhongbo Yang
Abstract
Molecular diagnostics has expanded to become the standard of care for a variety of solid tumor types. With limited diagnostic material, it is often desirable to use cytological preparations to provide rapid and accurate molecular results. This review covers important pre-analytic considerations and limitations, and a description of common techniques that the modern cytopathologist should understand when ordering and interpreting molecular tests in practice.
Topics & Concepts
MedicineCytologyMedical physicsMolecular diagnosticsComputational biologyPathologyBioinformaticsBiologyMolecular Biology Techniques and ApplicationsBacteriophages and microbial interactionsGene expression and cancer classification