Development of a rational strategy for integration of lactate dehydrogenase A suppression into therapeutic algorithms for head and neck cancer
Yunyun Chen, Anastasios Maniakas, Lin Tan, Meng Cui, Xiangdong Le, Joshua S. Niedzielski, Keith A. Michel, Collin Harlan, Wuhao Lu, Ying C. Henderson, Abdallah Mohamed, Philip L. Lorenzi, Nagireddy Putluri, James A. Bankson, Vlad C. Sandulache, Stephen Y. Lai
Topics & Concepts
Lactate dehydrogenase AGlycolysisHead and neck squamous-cell carcinomaCancer researchWarburg effectClonogenic assayLactate dehydrogenaseSmall hairpin RNACancer cellBiologyCancerHead and neck cancerCellInternal medicineMedicineBiochemistryMetabolismEnzymeGene knockdownApoptosisCancer, Hypoxia, and MetabolismCancer Research and TreatmentsCancer Cells and Metastasis