Novel natural scaffold as hURAT1 inhibitor identified by 3D-shape-based, docking-based virtual screening approach and biological evaluation
Xinhua Chen, Zean Zhao, Jiajun Luo, Ting Wu, Yu‐Dong Shen, Shan Chang, Shanhe Wan, Zhonghuang Li, Jiajie Zhang, Jianxin Pang, Yuanxin Tian
Topics & Concepts
ChemistryVirtual screeningScaffoldDocking (animal)Computational biologyDrug discoveryBiochemistryBiomedical engineeringEngineeringNursingMedicineBiologyNatural product bioactivities and synthesisUbiquitin and proteasome pathwaysPlant biochemistry and biosynthesis