Design, synthesis, and biological evaluation of novel dual PPARα/δ agonists for the treatment of T2DM
Qiang Ren, Liming Deng, Zongtao Zhou, Xuekun Wang, Lijun Hu, Rongrong Xie, Zheng Li
Topics & Concepts
ChemistryAgonistPPAR agonistPeroxisome proliferator-activated receptorRosiglitazonePharmacologyType 2 Diabetes MellitusPotencyReceptorDiabetes mellitusStereochemistryBiochemistryIn vitroEndocrinologyMedicinePeroxisome Proliferator-Activated ReceptorsNeuropeptides and Animal PhysiologyReceptor Mechanisms and Signaling