Visible-light-induced C–H sulfenylation of quinoxalin-2(1H)-ones with disulfides by sustainable cerium catalysis
Lixi Zhang, Jingwen He, Pengfei Zhang, Dancheng Zhu, Kai Zheng, Chao Shen
Abstract
Using visible light as energy to form free radicals has important synthetic value. A novel and efficient visible-light-mediated strategy has been developed for the generation of thiobenzene radicals through cerium-catalyzed activation of the disulfides. Through this photochemical reaction, various 3-sulfenylated quinoxalin-2(1H)-ones can be conveniently obtained in good yields with good functional group tolerance. Our transformation provides an alternative that allows rapid access to various C3 sulfenylated quinoxalin-2(1H)-ones in a sustainable and practical manner.
Topics & Concepts
CeriumRadicalCatalysisVisible spectrumChemistryCombinatorial chemistryPhotochemistryMaterials scienceOrganic chemistryOptoelectronicsSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsAdvanced Photocatalysis Techniques