Litcius/Paper detail

On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death

John A. Kucera, Douglas M. Overbey, Joseph W. Turek

2025New England Journal of Medicine15 citationsDOI

Abstract

Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list times and resultant deaths in this population. Donation after circulatory death (DCD) with normothermic regional perfusion has the potential to increase the donor pool by up to 30%. Ethical concerns have limited adoption of this technique in the United States and abroad. Consequently, a method facilitating ex vivo resuscitation of hearts from deceased donors after circulatory death (i.e., DCD hearts) is needed. We describe an on-table reanimation of a pediatric DCD heart transplanted into a 3-month-old recipient. Adverse events are reported.

Topics & Concepts

DonationTable (database)Organ donationCirculatory systemMedicineIntensive care medicineCardiologyInternal medicineTransplantationComputer sciencePolitical scienceLawData miningCardiac Arrest and ResuscitationMechanical Circulatory Support DevicesOrgan Transplantation Techniques and Outcomes