Vertical transmission of SARS-CoV-2: A systematic review
Kristine Jeganathan, Anthea B. Mahesan Paul
Abstract
In this study, we discuss vertical transmission of SARS-CoV-2, and assess various maternal and neonatal outcomes based on the current evidence available. This systematic review using PRISMA guidelines revealed a total of 47 eligible studies describing 1188 SARS-CoV-2 positive pregnant women and 985 neonates for review. Utilizing the ‘Shah’s Classification System for Maternal-Fetal-Neonatal SARS-CoV-2 Intrauterine Infections’ by Shah et al., we found vertical transmission confirmed in 0.3% ( n = 3), probable in 0.5% ( n = 5), possible in 1.8% ( n = 17), unlikely in 80.3% (724) and not infected in 17% ( n = 153).
Topics & Concepts
MedicineTransmission (telecommunications)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakObstetricsVirologyInternal medicineDiseaseEngineeringElectrical engineeringInfectious disease (medical specialty)OutbreakCOVID-19 Impact on ReproductionCOVID-19 and Mental HealthCOVID-19 and healthcare impacts