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Supercritical CO<sub>2</sub> assisted extraction of essential oil and naringin from <i>Citrus grandis</i> peel: <i>in vitro</i> antimicrobial activity and docking study

Thanh-Chi Mai, Ngoc-Thinh Tran, Dinh‐Tri Mai, Tran Thi Bich Ngoc, Duyen Hong Thuc Nguyen, Tran Nguyen Minh An, Mahboob Alam, Chi–Hien Dang, Thanh–Danh Nguyen

2022RSC Advances24 citationsDOIOpen Access PDF

Abstract

well and that naringin possessed potential ligand interactions that proved the inhibition effective against fungi. Molecular dynamics simulations of naringin demonstrated the best docking model using Gromacs during simulation up to 100 ns to explore the stability of the complex naringin and crystal structure of enzyme 2VF5: PDB.

Topics & Concepts

NaringinChemistryEssential oilAntimicrobialSupercritical fluidChromatographyAntibacterial activityExtraction (chemistry)Docking (animal)Food scienceOrganic chemistryBacteriaBiologyGeneticsMedicineNursingEssential Oils and Antimicrobial ActivityPhytochemical compounds biological activitiesPhytochemistry and Biological Activities
Supercritical CO<sub>2</sub> assisted extraction of essential oil and naringin from <i>Citrus grandis</i> peel: <i>in vitro</i> antimicrobial activity and docking study | Litcius