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Three versus six cycles of platinum-based chemotherapy followed by avelumab maintenance as first-line treatment for advanced urothelial cancer: the phase II DISCUS trial

T. Powles, S.A. Hussain, M.Á. Climent, Iciar Garcı́a Carbonero, Javier Molina‐Cerrillo, J. Puente, Pablo Borrega, Jeffrey Malik, Louis-Marie Dourthe, R. Jones, D Castellano, Ignacio Durán, Yohann Loriot, G. Priyadarshini, Bernadett Szabados, F. Jamal, Y.Q. Wang, Nishtha Kotriwala, F. Jackson-Spence, C. Ackerman, E. Grande

2025Annals of Oncology6 citationsDOIOpen Access PDF

Topics & Concepts

AvelumabMedicineChemotherapyMaintenance therapyInternal medicineOncologyRandomized controlled trialUrothelial cancerChemotherapy regimenClinical trialPhases of clinical researchSurgeryImmunotherapyUrologyRandomizationProgression-free survivalBladder and Urothelial Cancer TreatmentsRenal cell carcinoma treatmentIntraperitoneal and Appendiceal Malignancies
Three versus six cycles of platinum-based chemotherapy followed by avelumab maintenance as first-line treatment for advanced urothelial cancer: the phase II DISCUS trial | Litcius