NRG1 and NRG2 fusion positive solid tumor malignancies: a paradigm of ligand-fusion oncogenesis
Misako Nagasaka, Sai‐Hong Ignatius Ou
Topics & Concepts
CarcinogenesisNeuregulin 1NeuregulinFusion proteinCell biologyLigand (biochemistry)Cancer researchBiologyTransmembrane proteinReceptorEpidermal growth factor receptorEpidermal growth factorChemistrySignal transductionCancerBiochemistryGeneticsGeneRecombinant DNAHER2/EGFR in Cancer ResearchMonoclonal and Polyclonal Antibodies ResearchGlycosylation and Glycoproteins Research