An update on the molecular mechanism and pharmacological interventions for Ischemia-reperfusion injury by regulating AMPK/mTOR signaling pathway in autophagy
Bin Tang, Zhijian Luo, Rong Zhang, Dongmei Zhang, Guojun Nie, Mingxing Li, Yan Dai
Topics & Concepts
AutophagyAMPKPI3K/AKT/mTOR pathwayMechanistic target of rapamycinCell biologySignal transductionProtein kinase AmTORC2RPTORReperfusion injuryAMP-activated protein kinaseBiologyKinasemTORC1MedicineApoptosisIschemiaInternal medicineBiochemistryAutophagy in Disease and TherapyMetabolism, Diabetes, and CancerParkinson's Disease Mechanisms and Treatments