Rational design of stable heptamethine cyanines and development of a biomarker-activatable probe for detecting acute lung/kidney injuries <i>via</i> NIR-II fluorescence imaging
Juan Ouyang, Lihe Sun, Fang Zeng, Shuizhu Wu
Abstract
was subsequently evaluated in murine models of acute lung injury and acute kidney injury. This strategy unlocks the potential of heptamethine cyanines and is applicable to examples with extended conjugation.
Topics & Concepts
FluorescenceAnalyteCyanineFluorescence-lifetime imaging microscopyChemistryPhotochemistrySteric effectsMaterials scienceChromatographyOrganic chemistryOpticsPhysicsNanoplatforms for cancer theranosticsSulfur Compounds in BiologyLuminescence and Fluorescent Materials