Metabolite-driven antitumor immunity
James A. Nathan
Abstract
An oncometabolite blocks T cell killing by inhibiting glycolysis.
Topics & Concepts
MetaboliteImmunityChemistryBiologyImmune systemComputational biologyBiochemistryImmunologyCancer, Hypoxia, and MetabolismAutophagy in Disease and TherapyUbiquitin and proteasome pathways