Nanotechnology based gas delivery system: a “green” strategy for cancer diagnosis and treatment
Meixu Chen, Tianyue Xu, Linlin Song, Ting Sun, Zihan Xu, Yujie Zhao, Peixin Du, Ling Xiong, Zhankun Yang, Jing Jing, Hubing Shi
Abstract
), and heavier gases. The selection of optimal delivery vectors is also scrutinized in this review to ensure the efficacy of gaseous agents. The paper highlights the importance of engineering stimulus-responsive delivery systems that enable precise and targeted gas release, thereby augmenting the therapeutic efficiency of gas therapy. Additionally, the review examines the synergistic potential of integrating gas therapy with conventional treatments such as starvation therapy, ultrasound (US) therapy, chemotherapy, radiotherapy (RT), and photodynamic therapy (PDT). It also discusses the burgeoning role of advanced multimodal and US imaging in enhancing the precision of gas therapy applications. The insights presented are pivotal in the strategic development of nanomedicine platforms designed for the site-specific delivery of therapeutic gases, heralding a new era in cancer therapeutics.