Immune response gene 1 deficiency impairs Nrf2 activation and aggravates liver fibrosis in mice
Kerui Fan, Xinyan Zan, Ying Zhi, Yongqiang Yang, Kai Hu, Xinyue Zhang, Xue Zhang, Shuang Zhao, Kun Chen, Xianqiong Gong, Rui Tian, Li Zhang
Topics & Concepts
Downregulation and upregulationHepatic fibrosisFibrosisHydroxyprolineImmune systemEndocrinologyInternal medicineOxidative stressPathologicalLiver functionCCL4BiologyMedicineCarbon tetrachlorideImmunologyChemistryGeneBiochemistryOrganic chemistryLiver Disease Diagnosis and TreatmentLiver physiology and pathologyDrug-Induced Hepatotoxicity and Protection