Role of microRNA dysregulation in childhood acute leukemias: diagnostics, monitoring and therapeutics: A comprehensive review
Joanna Szczepanek
Abstract
., miR-125b and miR-223 for doxorubicin, miR-335 and miR-1208 for prednisolone, and miR-203 for imatinib), uncovering miRNAs that are associated with treatment response. In the current review, the role of miRNAs in the development, progression, and therapy monitoring of pediatric ALs will be presented and discussed.
Topics & Concepts
microRNAMedicineCancer researchBioinformaticsOncologyGeneBiologyGeneticsMicroRNA in disease regulationCircular RNAs in diseasesRNA Interference and Gene Delivery