Intraperitoneal administration of carcinoembryonic antigen-directed chimeric antigen receptor T cells is a robust delivery route for effective treatment of peritoneal carcinomatosis from colorectal cancer in pre-clinical study
Siyuan Qian, Jun Chen, Yongchun Zhao, Xiuxiu Zhu, Depeng Dai, Lei Qin, Juan Hong, Yanming Xu, Zhi Yang, Yunyan Li, Ismael Guijo, Santos Jiménez-Galanes, Héctor Guadalajara, Mariano García-Arranz, Damián García‐Olmo, Junjie Shen, Pedro Villarejo‐Campos, Cheng Qian
Topics & Concepts
Carcinoembryonic antigenMedicineChimeric antigen receptorMetastasisAntigenCancer researchColorectal cancerSystemic administrationCancer cellCancerImmunologyImmunotherapyInternal medicineIn vivoBiologyBiotechnologyCAR-T cell therapy researchCancer Immunotherapy and BiomarkersCancer Cells and Metastasis