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Design, synthesis and biological evaluation of N-(4-alkoxy-3-(1H-tetrazol-1-yl)phenyl) heterocyclic aromatic amide derivatives as xanthine oxidase inhibitors

Tingjian Zhang, Zhen-hao Zhang, Xu Zhang, Zhaoran Wang, Enyu Xu, Shun Tu, Yi Zhang, Fan‐hao Meng

2022Bioorganic Chemistry12 citationsDOI

Topics & Concepts

ChemistryXanthine oxidaseStereochemistryAmideImidazoleCarboxamideHydrogen bondLead compoundDocking (animal)EnzymeOrganic chemistryMoleculeBiochemistryIn vitroMedicineNursingGout, Hyperuricemia, Uric AcidPharmacological Effects of Natural CompoundsHepatitis C virus research
Design, synthesis and biological evaluation of N-(4-alkoxy-3-(1H-tetrazol-1-yl)phenyl) heterocyclic aromatic amide derivatives as xanthine oxidase inhibitors | Litcius