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Ruthenium-catalyzed dehydrogenative cyclization to synthesize polysubstituted 4-quinolones under solvent-free conditions

Bitan Sardar, Debjyoti Pal, Rajashri Sarmah, Dipankar Srimani

2023Chemical Communications10 citationsDOI

Abstract

Herein, we describe acridine-based SNS-Ru pincer-catalysed unprecedented dehydrogenative annulation of alcohols with 2′-aminoacetophenone to synthesize 2,3-disubstituted-4-quinolones.

Topics & Concepts

AnnulationChemistryRutheniumCombinatorial chemistryAlkylationCatalysisSolventAcridinePincer movementOrganic chemistryAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization MethodsSynthesis and Catalytic Reactions
Ruthenium-catalyzed dehydrogenative cyclization to synthesize polysubstituted 4-quinolones under solvent-free conditions | Litcius