Nucleophilic aromatic substitution reactions under aqueous, mild conditions using polymeric additive HPMC
Niginia Borlinghaus, Tharique N. Ansari, Leon H. von Garrel, Deborah Ogulu, Sachin Handa, Valentin Wittmann, Wilfried M. Braje
Abstract
A general, efficient, and sustainable method for nucleophilic aromatic substitution reactions in water using a cellulose-based additive was developed.
Topics & Concepts
Nucleophilic substitutionNucleophilic aromatic substitutionChemistrySubstitution reactionAqueous solutionCelluloseSubstitution (logic)Organic chemistryNucleophileRadical-nucleophilic aromatic substitutionCatalysisProgramming languageComputer scienceChemistry and Chemical EngineeringMulticomponent Synthesis of HeterocyclesChemical Synthesis and Reactions