A innovative prognostic symbol based on neutrophil extracellular traps (NETs)-related lncRNA signature in non-small-cell lung cancer
Fang Chen, Fen Liu, Yong Wang, Shangkun Yuan, Renfang Chen, Xiaotong Qiu, Xiaoying Qian, Xinwei Zhang, Zhehao Xiao, Qian Wang, Biqi Fu, Yong Li
Abstract
< 0.001). Additionally, by RT-qPCR, we confirmed that NSCLC cell lines have higher levels of the three adverse prognostic NETs-related lncRNAs than normal lung cells. The expression of lncRNAs significantly increases after NETs stimulation. In short, the 12 NETs-related lncRNAs and their model could play effective roles as molecular markers in predicting survival for NSCLC patients.
Topics & Concepts
Neutrophil extracellular trapsSignature (topology)Symbol (formal)LungCancerMedicineLung infectionCellOncologyComputer scienceInternal medicineBiologyInflammationMathematicsGeneticsGeometryProgramming languageNeutrophil, Myeloperoxidase and Oxidative MechanismsCancer-related molecular mechanisms researchImmune cells in cancer