Recent developments in nickel-catalyzed asymmetric cyclization and cycloaddition of carbonyl-alkynes, cyano-alkynes, and enynes
Jun Yan, Min Shi, Yin Wei
Abstract
Alkynes as unsaturated hydrocarbons have long been used for cyclization reactions. Various transition metal-catalyzed cyclizations of alkynes have been reported in the past decades. In this minireview, we mainly summarize the recent asymmetric cyclization of alkynes with other functional groups such as carbonyl-alkynes, cyano-alkynes, and enynes under the catalytic system of nickel and chiral ligands.
Topics & Concepts
CycloadditionCatalysisNickelChemistryCombinatorial chemistryMedicinal chemistryOrganic chemistryCatalytic Alkyne ReactionsCatalytic C–H Functionalization MethodsCyclopropane Reaction Mechanisms