Intermolecular through‐space charge transfer enabled by bicomponent assembly for ultrasensitive detection of synthetic cannabinoid JWH‐018
Chaogan Liu, Fangfang Xiao, Yushu Li, Da Lei, Yuan Liu, Xiaowei Ma, Chengzhi Gu, Xincun Dou
Abstract
Abstract Launching the intermolecular through‐space charge transfer (TSCT) from a bicomponent assembly for photophysical property manipulation is of great significance in fluorescence probe design. Here, we demonstrate the elaborate control of droplet evaporation dynamics for intermolecular TSCT can facilitate the ultrasensitive detection of JWH‐018, a representative synthetic cannabinoid. Driven by diverse intermolecular interactions, the probe, and JWH‐018 assemble in a closely stacked manner to emit strong fluorescence at 477 nm, ascribing to the intermolecular TSCT at the S 2 state. The strategy realizes an ultra‐low limit of detection of 11 nmol/mL and great selectivity towards JWH‐018. The practicability is further verified by constructing a sensing chip for JWH‐018 aerosol detection, which facilitates the on‐site drug abuser screening with the naked eye. Moreover, the proposed assembly‐enabled TSCT is expected to find a variety of applications for optoelectronic materials design and photophysical mechanism‐dominated molecular recognition.