Ultrasound enhanced siRNA delivery using cationic liposome-microbubble complexes for the treatment of squamous cell carcinoma
Bin Qin, Xucai Chen, Jianhui Zhu, Jonathan A. Kopechek, Brandon Helfield, François T.H. Yu, Jissy Cyriac, Linda Lavery, Jennifer R. Grandis, Flordeliza S. Villanueva
Abstract
, suggesting that this platform holds promise for non-invasive, image-guided targeted delivery of therapeutic siRNA for cancer treatment.
Topics & Concepts
LuciferaseIn vivoCationic liposomeChemistrySmall interfering RNALiposomeMolecular biologyCancer researchMedicineTransfectionBiologyBiochemistryGeneBiotechnologyUltrasound and Hyperthermia ApplicationsUltrasound and Cavitation PhenomenaRNA Interference and Gene Delivery