A new perspective in cancer immunotherapy: PD-1 on myeloid cells takes center stage in orchestrating immune checkpoint blockade
Christopher E. Rudd
Abstract
PD-1 mediates antitumor immunity by regulating lineage fate commitment and function of myeloid cells (see the related Research Article by Strauss et al. ).
Topics & Concepts
BlockadeImmune checkpointImmunotherapyCancer immunotherapyMyeloid cellsStage (stratigraphy)Cancer researchImmune systemPerspective (graphical)PD-L1MyeloidImmunologyBiologyMedicineInternal medicineComputer scienceReceptorPaleontologyArtificial intelligenceCancer Immunotherapy and BiomarkersImmune Cell Function and InteractionImmune cells in cancer