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An SGLT2 inhibitor modulates SHH expression by activating AMPK to inhibit the migration and induce the apoptosis of cervical carcinoma cells

Zipeng Xie, Fang Wang, Lingqiang Lin, Shaoxian Duan, Xiangyang Liu, Xiaoyu Li, Ting Li, Mei Xue, Ying Cheng, He Ren, Yi Zhu

2020Cancer Letters75 citationsDOI

Topics & Concepts

EmpagliflozinAMPKDownregulation and upregulationApoptosisCancer researchSmall interfering RNAFOXA1ChemistryCancerMedicineEndocrinologyTransfectionProtein kinase AInternal medicineKinaseDiabetes mellitusBiochemistryType 2 diabetesBreast cancerGeneHedgehog Signaling Pathway StudiesPancreatic and Hepatic Oncology ResearchCancer-related Molecular Pathways
An SGLT2 inhibitor modulates SHH expression by activating AMPK to inhibit the migration and induce the apoptosis of cervical carcinoma cells | Litcius